Odds, point spreads released for opening week of college football 2022

With less than three months left until the first kickoff of the 2022 college football season, Las Vegas has released odds and point spreads for every Week 0/Week 1 game.

Ohio State and Notre Dame will have a ton of eyeballs for their 2022 season-opening matchup in Columbus on Sept. 3. The marquee matchup got the 7:30 p.m. slot on ABC opening weekend and College GameDay will host from the Ohio State campus.

On top of Ohio State-Notre Dame, the opening Saturday of the season has several key matchups like Oregon–Georgia, Arkansas–Cincinnati, Utah–Florida and more.

Check out the full list of Week 0 and Week 1 spreads, courtesy of Vegas Insider. Games without available odds are not included.

Aug. 27 Game Odds

Nebraska (-12.5) vs. Northwestern
Wyoming vs. Illinois (-11)
Vanderbilt (-6.5) vs. Hawaii
Nevada (-13.5) vs. New Mexico State
UConn vs. Utah State (-27.5)
Florida Atlantic (-7.5) vs. Charlotte
North Texas (-2) vs. UTEP

Sept. 1 Games

Tennessee (-30.5) vs. Ball State
West Virginia vs. Pittsburgh (-7.5)
Central Michigan vs. Oklahoma State (-20.5)
Purdue vs. Penn State (-3.5)
Louisiana Tech vs. Missouri (-18.5)
Minnesota (-38.5) vs. New Mexico State

Sept. 2 Games

Virginia Tech (-8.5) vs. Old Dominion
Michigan State (-18.5) vs. Western Michigan
Duke (-8) vs. Temple
Illinois vs. Indiana (-5.5)
TCU (-7.5) vs. Colorado

Kickoff Saturday Sept. 3 Odds

Ohio State (-14.5) vs. Notre Dame
Georgia (-18.5) vs. Oregon (Atlanta)
Florida vs. Utah (-1.5)
Arkansas (-6.5) vs. Cincinnati
LSU (-3.5) vs. Florida State (New Orleans)
Clemson (-21.5) vs. Georgia Tech
Alabama (-38.5) vs. Utah State
Memphis vs. Mississippi State (-16.5)
ULM vs. Texas (-38.5)
Western Kentucky (-11) vs. Hawaii
Texas State vs. Nevada (-7.5)
Maryland (-21.5) vs. Buffalo
Colorado State vs. Michigan (-27.5)
North Carolina (-3.5) vs. Appalachian State
NC State (-10.5) vs. East Carolina
Rutgers vs. Boston College (-7.5)
Bowling Green vs. UCLA (-26.5)
UTEP vs. Oklahoma (-32.5)
Houston (-4.5) vs. UTSA
Tulsa (-1.5) vs. Wyoming
Arizona vs. San Diego St. (-5)
BYU (-12.5) vs. USF
Troy vs. Ole Miss (-23.5)
Rice vs. USC (-35.5)
FAU (-2.5) vs. Ohio
Miami (OH) vs. Kentucky (-12.5)
UMass vs. Tulane (-29.5)
Army vs. Coastal Carolina (-4)
Liberty (-3.5) vs. Southern Miss
Georgia State vs. South Carolina (-13.5)
SMU (-8.5) vs. North Texas
Louisville (-3.5) vs. Syracuse
Kent State vs. Washington (-22)
Boise State vs. Oregon State (-3.5)