Week 4 college football odds: Las Vegas releases point spreads for weekend slate

On3 imageby:Jonathan Wagner09/19/21

Jonathan Wagner

Week three was another entertaining one for college football. After a few upsets and a lot of entertaining matchups between Top 25 teams, there was some movement in the AP Top 25 Poll ahead of Week 4. Vegas Insider has also released its opening betting odds for the Week 4 slate.

Week 4 contains a few interesting matchups across the country. At noon, No. 12 Notre Dame takes on No. 18 Wisconsin. No. 16 Arkansas also hosts No. 7 Texas A&M in the only other matchup between two Top 25 teams on the weekend.

There are many other intriguing matchups in Week 4, including Texas vs. Texas Tech, Clemson vs. NC State, Mississippi State vs. LSU, and Florida-Tennessee, among many others.

Some Top 25 teams are looking for big bounce-back games in Week 4. Oklahoma closely snuck by Nebraska, and that was the same story for Ohio State over Tulsa. Clemson also struggled, defeating Georgia Tech just 14-8.

UCLA is also looking to come back strong after falling to Fresno State. The Bruins were high risers in recent weeks, but Saturday’s loss was a huge setback for UCLA’s high hopes.

Week 4’s opening odds

Wake Forest at Virginia (-4.5)
Liberty (-7) at Syracuse
Bowling Green State at Minnesota (-31)
Kentucky (-5.5) at South Carolina
Notre Dame at Wisconsin (-5)
Kent State at Maryland (-14.5)
Illinois at Purdue (-10.5)
Akron at Ohio State (-49)
Kansas at Duke (-13)
Missouri (-1.5) at Boston College
Ohio at Northwestern (-14)
North Carolina (-12.5) at Georgia Tech
Colorado State at Iowa (-22)
Indiana (-10) at Western Kentucky
Washington State at Utah (-14)
Colorado at Arizona State (-15)
UCLA (-4) at Stanford
Oregon State at USC (-13)
Louisville (-2) at Florida State
Kansas State at Oklahoma State (-8)
Southern Miss at Alabama (-44.5)
Georgia (-32.5) at Vanderbilt
West Virginia at Oklahoma (-19.5)
LSU (-5) at Mississippi State
Texas Tech at Texas (-11)
SMU at TCU (-10.5)
Iowa State (-6) at Baylor
Tennessee at Florida (-16.5)
Clemson (-12) at NC State
Nebraska at Michigan State (-3.5)
Rutgers at Michigan (-19)
Georgia State at Auburn (-24)
California at Washington (-8)
Arizona at Oregon (-27)

Week 4 gets underway with Marshall at Appalachian State on Thursday night. There are four games on Friday’s slate.