Kyler Murray injury update: Jonathan Gannon rules Cardinals QB out for remainder of season

Kyler Murray won’t be returning in 2025. According to Cardinals head coach Jonathan Gannon, the Arizona quarterback had some tests out of state on his foot. It’s not progressing enough to warrant a return to the starting lineup, per Darren Urban.

Murray hasn’t played since suffering the foot injury in Week 5 against the Tennessee Titans. At first, the Cardinals hoped he could return. He was labeled a game-time decision the next week, but the setback lingered. 

Murray ultimately missed three straight games before landing on injured reserve, ending a season that saw him appear in just five contests. In those outings, he completed 110 of 161 passes for 962 yards, six touchdowns and three interceptions, posting a passer rating of 88.6. He also rushed for 173 yards and a touchdown on 29 carries.

Gannon explained that the team’s decision was based on both performance and health at the time. However, injuries will prohibit his return to the team: “He wasn’t progressing in a way that we wanted, so we went and got a different opinion, some different people, and the foot is just not right,” he said. 

That evaluation has coincided with Gannon turning the offense over to veteran Jacoby Brissett. The signal that Murray’s season was headed toward an abrupt end. Murray himself helped break the silence on Thursday. He posted a photo with teammates on social media and captioned it, “Weird Year. … Never again.”

Is this the end of Kyler Murray in Arizona?

Now, attention turns to what this means for Murray’s future, and perhaps Gannon’s as well. The quarterback’s durability and contract situation have been talking points for months. His prolonged absence will only renew speculation about whether he’ll still be Arizona’s franchise quarterback in 2026. 

Gannon brushed aside that conversation, saying his focus is solely on this week’s matchup against the Rams. Still, it’s clear the organization faces major decisions. 

Moreover, Gannon’s own job security has been discussed in recent weeks. If the Cardinals do make a coaching change, a new staff could have a very different vision for how to structure the offense moving forward.

As for the present, Gannon praised his team and staff for staying steady through a turbulent stretch: “That’s the job,” he said of handling injuries. “You have to figure it out. Our job is to have solutions and be part of the solution, not part of the problem.”

Murray’s “weird year” is now officially over. As for the biggest questions surrounding Arizona’s future? Those are just beginning, and time will tell if the quarterback remains in town in 2026.