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Penn State-Northwestern predictions: How computer data systems, college football experts, see the game

Greg Pickelby: Greg Pickel10/11/25GregPickel
NCAA Football: Villanova at Penn State
Sep 13, 2025; University Park, Pennsylvania, USA; Penn State Nittany Lions running back Kaytron Allen (13) runs with the ball into the end zone for a touchdown during the fourth quarter against the Villanova Wildcats at Beaver Stadium. Mandatory Credit: Matthew O'Haren-Imagn Images

Penn State is a three-touchdown favorite for Saturday's matchup with Northwestern. Will the Lions cover? We tell you here.