Ebola Vaccines - Exotic and Pressed Into Service

[CastleRubric]

So a previous career chapter results in my having a lingering interest in epidemiology ...
I spent a few hours this past Saturday checking up on one of my favorite niche subjects ,,,,, vaccine development issues for Ebola and the “universal flu” shot that’s coming soon too

Right now there are about TWELVE different types of Ebola vaccines being tested on the human in the Congo ....

Add to that additional efforts coming from China and Russia as well

https://pharmaintelligence.informa....action-chinas-best-shot-in-ebola-vaccine-race

http://www.mid.ru/en_GB/foreign_policy/news/-/asset_publisher/cKNonkJE02Bw/content/id/2838077

Merck currently has the one that’s getting the most attention because of their impressive claim of how it created “total immunity” when thy tested it in Guinea
Edit: while this vaccine is getting the most attention right now because “it performed so well in the 2015 Guinea outbreak “....there’s a surprising lack of data and valid scientific criticism stating that the trial-vaccine was introduced at the end of the outbreak and wasn’t as effective as advertised...

Source: https://www.sciencemag.org/news/2018/05/research-during-ebola-vaccine-trial-it-s-complicated

Note that waivers are in place since these vaccines haven’t been fully vetted through clinical/human trials

https://pharmaphorum.com/news/merck-co-begins-us-filing-of-ebola-vaccine/

There’s another version that’s genetically combined with a strain of rabies ....Ebola and Rabies — YES !!! Finally!!!

https://www.cdcfoundation.org/what/program/evaluation-rabies-virus-vectored-ebola-vaccine

And more recently:

https://www.ncbi.nlm.nih.gov/m/pubmed/28822816/

Post would be too long if I tried to remember all the factoids so here are some links for the curious

Only side effects I could find were body aches- and skin lesions...that could last one to two years

The largest ever outbreak of Ebola happend around 2014-2015

We’re currently experiencing the second largest outbreak ever

Not to be confused with Ebola-ramen from Japan [sick]

 

[CastleRubric]

https://www.historyofvaccines.org/content/articles/ebola-virus-disease-and-ebola-vaccinesOne more- university of Kentucky was supporting some of the research at one time ....

Seems that one of you looney yahoos decided to try and grow vaccine proteins (?)....on tobacco leaves

https://www.pbs.org/newshour/show/how-to-grow-an-ebola-vaccine-with-a-tobacco-plant

Major points for making tobacco a life saver as well as a taker ....while possibly boosting the local economy at the same time :fistbump:


Finally - the investigative vaccine that combines Ebola with rabies originates from Thomas Jefferson University...with significant support coming from the US Department of Defense

A vaccine candidate originating from Thomas Jefferson University's Vaccine Center may advance to clinical trials in humans. This vaccine, developed by Jefferson's Matthias Schnell, delivers Ebola antigens with an inactivated rabies virus vector. Versions of the vaccine, which have also delivered both Ebola Zaire and Ebola Sudan antigens as well as Marburg virus antigens, have been tested in macaques. Funding from the National Institute of Allergy and Infectious Diseases and the Department of Defense allowed production of a clinical lot of the vaccine for a potential Phase 1 trial

 

[UKGrad93]

Let me know when we have a vaccine for Rhinovirus.

 

[KentuckyStout]

Obviously you've read The Hot Zone Rubric? Ebola Zaire I think - nearly got out in the US from the Reston (Va.) Monkey House.

Big problem with these virus' is their ability to change their molecular structure and render old vaccines obsolete.

 

[-Mav-]

I thought e-Bola was a computer virus.

 

[KyCatFan_rivals45723]

Who would want to be a test subject during trials for an ebola vaccine? I'm not signing up for that one.

 

[FutureCityCats_rivals]

So a previous career chapter results in my having a lingering interest in epidemiology ...
I spent a few hours this past Saturday checking up on one of my favorite niche subjects ,,,,, vaccine development issues for Ebola and the “universal flu” shot that’s coming soon too

Right now there are about TWELVE different types of Ebola vaccines being tested on the human in the Congo ....

Add to that additional efforts coming from China and Russia as well

https://pharmaintelligence.informa....action-chinas-best-shot-in-ebola-vaccine-race

http://www.mid.ru/en_GB/foreign_policy/news/-/asset_publisher/cKNonkJE02Bw/content/id/2838077

Merck currently has the one that’s getting the most attention because of their impressive claim of how it created “total immunity” when thy tested it in Guinea
Edit: while this vaccine is getting the most attention right now because “it performed so well in the 2015 Guinea outbreak “....there’s a surprising lack of data and valid scientific criticism stating that the trial-vaccine was introduced at the end of the outbreak and wasn’t as effective as advertised...

Source: https://www.sciencemag.org/news/2018/05/research-during-ebola-vaccine-trial-it-s-complicated

Note that waivers are in place since these vaccines haven’t been fully vetted through clinical/human trials

https://pharmaphorum.com/news/merck-co-begins-us-filing-of-ebola-vaccine/

There’s another version that’s genetically combined with a strain of rabies ....Ebola and Rabies — YES !!! Finally!!!

https://www.cdcfoundation.org/what/program/evaluation-rabies-virus-vectored-ebola-vaccine

And more recently:

https://www.ncbi.nlm.nih.gov/m/pubmed/28822816/

Post would be too long if I tried to remember all the factoids so here are some links for the curious

Only side effects I could find were body aches- and skin lesions...that could last one to two years

The largest ever outbreak of Ebola happend around 2014-2015

We’re currently experiencing the second largest outbreak ever

Not to be confused with Ebola-ramen from Japan [sick]

Thanks castlerubic for the info. Good stuff. Merck has been around for awhile. And even though you can pick apart any experiment, I'm sure they had good data. Even so it makes you wonder whether it's money driven or actual healing results.

Antigen vs. antibody. Our immune system is brutal and fascinating. FCC.

 

[thabigbluenation]

We are going to do this to ourselves one day