Notre Dame at Pittsburgh odds: Opening point spread revealed, How to Watch

No. 10 Notre Dame and No. 24 Pittsburgh are set to clash in a Week 12 non-conference matchup, with the game taking place at Acrisure Stadium in Pittsburgh, PA. Notre Dame is coming off an 49-X10 home victory over Navy (marking its seventh consecutive win after opening the season 0-2), while Pittsburgh enjoyed a bye-week riding high on a five-game winning streak.

Ahead of Week 12’s matchup, the early point spread and more have been revealed. All odds are courtesy of BetMGM. Notre Dame has opened as a 10.5-point favorite over Pittsburgh. The over/under is set at 56.5 points.

These programs met in 2023 and have previously met 72 times dating back to 1909. No. 14 Notre Dame rolled Pittsburgh 58-7 in South Bend thanks to three rushing touchdowns from Fighting Irish running back Audric Estime. Notre Dame lead the all-time series 50-21-1 and has won four consecutive meetings dating back to 2015.

How to watch No. 10 Notre Dame at Pittsburgh

Time: 12:00 p.m. ET
Channel: ACC Network
Location: Pittsburgh, PA

The Pittsburgh Panthers have been on fire since freshman quarterback Mason Heintschel took over the starting job against Boston College on Oct. 4. In that span, Pitt has outscored opponents 200-105 en route to a five-game winning streak. In five starts, Heintschel has passed for 1,511 yards and 12 touchdowns. He’s reached the 300-plus yard passing mark in four of those five games

Thanks to their recent success, the Panthers appeared at No. 24 in the first College Football Playoff Rankings of the season. Their opponent, Notre Dame, was placed at No. 10 in the CFP Rankings.

Notre Dame has now won seven consecutive games and has lowly Stanford and Syracuse remaining on the schedule following its game against Pittsburgh. If they can safely land the plane, the Irish look to be locks to return to the College Football Playoff with two losses on their resume.

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