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In the Balance: How Pitt Matches up Statistically with Louisville

NathanBreisingerby: Nathan Breisinger09/26/25NateBreisinger
Nov 23, 2024; Louisville, Kentucky, USA; Louisville Cardinals linebacker Stanquan Clark (6) and linebacker TJ Quinn (34) tackle Pittsburgh Panthers running back Desmond Reid (0) during the first half at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images
Nov 23, 2024; Louisville, Kentucky, USA; Louisville Cardinals linebacker Stanquan Clark (6) and linebacker TJ Quinn (34) tackle Pittsburgh Panthers running back Desmond Reid (0) during the first half at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images

Pitt football is set to face the Louisville Cardinals to kick off their respective ACC slates. The Panthers have an 11-10 all-time edge in the series, but the Cardinals won the most recent matchup between the two with a blow out 37-9 a year ago.