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Game Day Central: Syracuse Orange vs. Notre Dame football

Singer headshotby: Mike Singer11/22/25MikeTSinger

It’s senior day in South Bend. The No. 9 Notre Dame Fighting Irish (8-2) are set to host the struggling Syracuse Orange (3-7, 1-6 ACC) on Saturday afternoon. Notre Dame has won eight contests in the row, while the ‘Cuse are losers of six straight. Blue & Gold gets you ready with what you need to know before today’s tilt.

Join us live on YouTube after the game as we break down ND vs. Syracuse

GAME DAY INFORMATION

Date: Nov. 22, 2025
Site (Capacity): Notre Dame Stadium (77,622)
Kickoff: 3:30 p.m. ET
Television: NBC
Radio: This game can be heard on Notre Dame IMG affiliates.
Series Facts: Notre Dame leads 8-3. The Irish won the most recent meeting 41-24 in Syracuse, N.Y., on Oct. 29, 2022.
Head coaches: Syracuse — Fran Brown (13-10, 2nd season); Notre Dame — Marcus Freeman (41-12, 4th season).
Noting Syracuse: The Orange lost star tight end Oronde Gadsen II and Kyle McCord to the NFL Draft and several top players, including wide receiver Trebor Peña and defensive tackle Maraad Watson, to the transfer portal … Texas transfer Johntay Cook leads the Orange in receiving with 41 receptions for 518 yards … Syracuse is one of the worst turnover margin teams in the country, tied for 128th at minus-10.

Blue & Gold subscribers: Click here for the full game day package with depth charts, rosters, stats and more.

GAME PREDICTIONS

BetMGM line: Irish -35.5 …. Over/under 50.5

Eric Hansen: ND 44, Syracuse 6
Tyler Horka: ND 42, Syracuse 7
Tyler James: ND 41, Syracuse 13
Kyle Kelly: ND 56, Syracuse 10
Jack Soble: ND 42, Syracuse 7
Todd D. Burlage: ND 48, Syracuse 3
Steve Downey: ND 52, Syracuse 0
Mike Singer: ND 42, Syracuse 6

Full staff predictions article

PREGAME READING