Your passing game is set for years and that system will always produce a good running game. Denver's biggest need is up the middle, DT - Safeties.
As for Indy, I can tell you right now they aren't excited about this game. SD has won 3 out of the last 4 and every game has been close.
Nov 23, 2008 IND 23, @SD 20
Jan 13, 2008 SD 28, @IND 24
Nov 11, 2007 @SD 23, IND 21
Dec 18, 2005 SD 26, @IND 17
Dec 26, 2004 @IND 34, SD 31
Peyton is on top of his game right now, but so is Rivers and LT. The key will be how much Bob Sanders will contribute. SD just has an overload of riches at the skill positions. Rivers, a douche he may be, is a hell of a QB and a competitor. LT. Gates. Vincent Jackson is a freak, Chambers, Legadu Nanee is probably the best player in the league that most people haven't heard of.