I second Spice Market, if you're into palate pleasing adventures.  If you're not familiar with SE Asian cuisine ask the waiter for suggestions of popular dishes.  These guys/gals know what gets ordered regularly.  If you or anyone in your party is more into plain old meat and potatoes or looking for the chicken cutlet entree stay away.  Most importantly, if you plan on doing Meat Packing reserve well in advance.  Lastly, I would not do Italian in the Meat Packing Distric.  You can get similar food anywhere else in the city for half the price.  But yes, there are several well reviewed Italian restaurants and I've been to a few of them, but none have impressed me.