Having lived and worked in Houston for 30 years - including off Eldridge by Lupe Tortilla -there are a number of good places along the I-10 feeder road strip headed back toward Houston. Not sure how many are ones that you should "definitely hit", but there are the Taste of Texas Steak House, Pappasitos (TexMex), Pappadeaux (seafood) and a couple of steak housesright next to the Memorial Mall, also on the same feeder road headed back to Houston. Most of the really good places (that are not downtown) to eat are on Westheimer between beltway 8 and the Montrose area. Ruggles, Americas (San Felipe), Churrascos, Cheesecake Factory,La Strada to name just a few. A little pricier, but pretty good food nonetheless.