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ESPN College GameDay: Picks for Week 7, Indiana at Oregon

IMG_6598by: Nick Kosko10/11/25nickkosko59
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Ben Lonergan/The Register-Guard / USA TODAY NETWORK via Imagn Images

ESPN’s College GameDay stopped in Eugene for the IndianaOregon matchup, a top 10 one, in the Big Ten Saturday. Week 7 promises to give college football fans a lot of bangers across the slate.

Oregon is ranked No. 3 in the country at 5-0 while Indiana is rolling again, also at 5-0, and ranked No. 7 in the country. No wonder College GameDay chose the Pacific Northwest this weekend.

Kirk Herbstreit, Desmond Howard, Nick Saban, Pat McAfee and Celebrity Guest Picker, former Oregon basketball star Sabrina Ionescu, are ready to lock in their predictions. Check them out in full below, and see if you agree with their commentary for Saturday’s top showdowns.

ESPN College GameDay Picks for Week 7

Indiana at Oregon (GameDay Location): A lot of Oregon green and of course Ionescu saved her best analysis for last: “Ducks by a million.” McAfee already took his shirt off with Dan Lanning earlier in the morning and he also picked Indiana to wrap it up to turn heel!

Wake Forest at Oregon State: We had a clean sweep for Wake Forest in this one. No love lost for the Beavers while doing the show from Eugene.

Kansas at Texas Tech: Another clean sweep there for the Red Raiders. Basically, Kansas had no shot in this one according to the panel!

BYU at Arizona: What is going on here? Three sweeps in a row to open the picks segment. Pat McAfee didn’t like that everyone picked BYU.

Arizona State at Utah: Ionescu broke the mold by picking Arizona State, despite no Sam Leavitt at QB. Otherwise, everyone picked the Utes.

Florida at Texas A&M: McAfee is a big fan of the Aggies, especially moving forward. Kyle Field is a real advantage, but Howard was the lone picker of Florida.

Oklahoma vs. Texas: This one was split without Herbie picking the game. Saban went against Steve Sarkisian while Ionescu is all in on Arch Manning.

Alabama at Missouri: Everyone picked Alabama in this one until Herbstreit flipped to Missouri to avoid a clean sweep. We’ll see won’t we?!

ATS: Ohio State (-15.5) at Illinois: Everyone except Ionescu likes Ohio State to cover over two touchdowns in this one. That’s a big line!

ATS: Michigan at USC (-2.5): Same logic as above as everyone picked the favorite except the former Oregon women’s basketball star. This is a big spot for two Big Ten teams battling for CFP resumes.

Full analyst picks for Week 7

Desmond Howard: Wake Forest, Texas Tech, BYU, Utah, Florida, Texas, Alabama, Ohio State, Michigan, Oregon

Nick Saban: Wake Forest, Texas Tech, BYU, Utah, Texas A&M, Oklahoma, Alabama, Ohio State, Michigan, Oregon

Celebrity Guest Picker – Sabrina Ionescu: Wake Forest, Texas Tech, BYU, Arizona State, Texas A&M, Texas, Alabama, Illinois, USC, Oregon

Pat McAfee: Wake Forest, Texas Tech, BYU, Utah, Texas A&M, Oklahoma, Alabama, Ohio State, Michigan, Indiana

Kirk Herbstreit: Wake Forest, Texas Tech, BYU, Utah, Texas A&M, No pick for Texas vs. Oklahoma, Missouri, Ohio State, USC, Oregon

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