Clemson at Pittsburgh odds: Early point spread released, How to Watch
Clemson and Pittsburgh are set for a pivotal ACC Showdown in Week 12 and the odds from FanDuel are in!
Clemson is coming off a 24-14 win against Virginia Tech last weekend. Meanwhile Pitt played the state’s other school Virginia and lost 24-19.
According to FanDuel, Clemson opened up as a 10.5 point favorite in this one. The total was set at 57.5 points.
If you want to bet the moneyline, Clemson is listed at -375 while Pittsburgh is listed at +290 if you want to bet straight up.
How to watch Clemson vs. Pittsburgh
Time: 12:00 p.m. ET
Channel: ESPN/Fubo TV (Streaming)
Location: Pittsburgh, Pennsylvania
Clemson was rolling until they suffered their second loss of the season. So when you compare Clemson to Pittsburgh, one would come away more impressed with Pitt this year.
That’s only due to the national title expectations of Dabo Swinney and Clemson. But after a loss to Louisville, ESPN’s Pete Thamel basically put the Tigers in the “upper middle class” of college football.
Top 10
- 1New
Bruce Pearl
Shreds Nate Oats over Bediako
- 2Hot
Top 10 QBs
Ranking QBs heading into 2026
- 3Trending
Charlie Woods
Tiger Woods' son commits to FSU
- 4
Top QB Battles
Quarterback races to watch
- 5
Sleeper QBs for 2026
Kirk Herbstreit makes picks
Get the Daily On3 Newsletter in your inbox every morning
By clicking "Subscribe to Newsletter", I agree to On3's Privacy Notice, Terms, and use of my personal information described therein.
However, they’re no longer a regular contender.
“I just don’t know what to make a Clemson this season,” Thamel said prior to Clemson’s game against Virginia Tech in Week 11. “The two times they’ve played formidable opponents, they’ve turtled. And in the other games, they’ve absolutely blitzed everybody. So, difficult situation.
“It’s never easy to play at Virginia Tech, even though this isn’t a vintage Virginia Tech team. Kyron Drones, the quarterback for Tech, has been practicing in full. They’re expecting him to come back this week. I want to see an authoritative performance by these Clemson Tigers. I want to see them dominate from end to end.”
Clemson’s other loss this season came against Georgia in Week 1 and it wasn’t particularly close. The Tigers fell 34-3 to the Bulldogs, only amassing 188 total yards of offense in the subpar showing.
Clemson and Pittsburgh had different trajectories coming into the season, but Pittsburgh didn’t suffer its first loss til a 48-25 loss to SMU on November 2nd.
How will Swinney fare against Pat Narduzzi’s crew? Well that remains to be seen so be sure to get your bets in!