Does MSFT security essentials not work with Win10? If it does, just use that because it's good enough, it's free and it's automatic. Nobody's AV is perfect, they all miss things. But whatever AV you use, you should be using a few other things if you want to be as secure as possible:
Purchase and install the pro version of Malwarebytes.
For web browsing:
(1) Use the Disconnect plugin (must be installed first)
(2) Use Firefox as your browser and use the NoScript plugin. NoScript prevents sites from running Javascript and allows you to selectively enable various scripts on any given site. And be parsimonious about which scripts you allow. Never allow more than necessary to do what you need to do at any given site and for sites that are not highly likely to be safe, don't allow any scripts to run.
(3) Use the ad-block plus plugin.
Of all those things, the thing that will do the most to keep you safe is NoScript. If you let any site run whatever Javascript it wants, then it doesn't really matter what AV software you have, you'll eventually get infected with stuff and you're constantly exposed. Let me put it like this: if you're not using NoScript, then I hope you're not doing online banking via your web browser because you're relying on luck and statistics to protect access to your accounts otherwise.