Been living here 5 years. I'm sure a lot of these have been mentioned, but:
- Butcher
Lunch or dinner. It's probably gonna be the meal you remember the most. Get the mac and cheese and then pick whatever sounds good to you. They have incredible daily and nightly specials, too. You'll wanna go back on your way outta town for some boudin to take home (or more).
- Peche
Dinner. Semi-casual atmosphere. Another Donald Link gem. They just won a James Beard Award. Get a whole fish.
- National WWII Museum
Recently expanded (and still expanding). You can spend hours in there. Tom Hanks narrated "4D" movie, expansive galleries, planes, tanks, landing crafts, a mock sub... the whole nine yards. DM if you actually plan on going and I can probably get your tickets comp'd (it's a little expensive).
- Frenchmen Street
Best spot for live music options. d.b.a. is my favorite bar. Expansive beer/liquor menu and always a good bet for great live music. If you're into soul food The Praline Connection is well-known and there but it won't knock your socks off (same for Mother's in the CBD). Frenchmen isn't really known for dining, although they did just get a Dat Dog, which is cluuuuuutch later at night.
- The Quarter
I mean, hell... you at least gotta show it to her. Bayona is my favorite restaurant in the Quarter. It's upscale but cozy. Get the veal sweetbreads. I know nothing about the haunted tours. People seem to like 'em? Swamp Tours can be cool, too. You'll find a brochure somewhere. I rode a steamboat down the Mississippi once, it was pretty. As for casual dining, nothing wrong with checking out Port of Call but Yo Mama's has better burgers. Central Grocery has been surpassed by Butcher on the muffuletta (in my opinion) but still cranks out huge, delicious stuff. They travel well, too.
- Parkway Bakery
If you want the best "we went to _____ for a real po-boy" experience. OR if you have an absurd appetite, go to Katie's (both are in Mid-City) and order "The Barge." They have good chargrilled oysters, too.
- Jacques-Imos's
It's in the Carrollton area if you want to go a little further off the beaten path (still easily accessible via street car or cab). After dinner you can go next door to the Maple Leaf for good live music.