Reading a book right now called "Outlive". It is pretty interesting. Exercise is by far the number one thing you can do for the "Four Horsemen":
In Peter Attia’s book Outlive, the "Four Horsemen" refer to the four major chronic diseases that are the leading causes of death and disability in aging populations. These are the conditions Attia believes we must proactively address to extend both lifespan and healthspan:
Attia argues that these diseases account for the vast majority of deaths in people over 50 who do not smoke. His approach, called Medicine 3.0, focuses on proactive, personalized prevention rather than reactive treatment [2].
Would you like a summary of how Attia recommends preventing each of these? Or maybe a breakdown of his "Centenarian Olympics" concept for aging well?
References
[1] 10 Takeaways from 'Outlive' by Peter Attia for Better Health
[2] Outlive by Peter Attia: A Book Review - Petrie-Flom Center
In Peter Attia’s book Outlive, the "Four Horsemen" refer to the four major chronic diseases that are the leading causes of death and disability in aging populations. These are the conditions Attia believes we must proactively address to extend both lifespan and healthspan:
The Four Horsemen of Chronic Disease (According to Outlive)
- Cardiovascular Disease (CVD)
- Includes heart attacks, strokes, and atherosclerosis.
- Attia emphasizes early detection and aggressive management of lipid markers like ApoB and LDL-C [1].
- Cancer
- Particularly those with long latency periods like colon, breast, and prostate cancer.
- Prevention strategies include lifestyle changes and early screening [1].
- Neurodegenerative Disease
- Most notably Alzheimer’s disease, but also includes Parkinson’s and other forms of dementia.
- Attia notes that patients fear cognitive decline more than any other condition [2].
- Metabolic Dysfunction
- Encompasses type 2 diabetes, insulin resistance, fatty liver disease, and obesity.
- Often underdiagnosed and linked to poor diet and sedentary lifestyle [1].
Why These Matter
Attia argues that these diseases account for the vast majority of deaths in people over 50 who do not smoke. His approach, called Medicine 3.0, focuses on proactive, personalized prevention rather than reactive treatment [2].Would you like a summary of how Attia recommends preventing each of these? Or maybe a breakdown of his "Centenarian Olympics" concept for aging well?
References
[1] 10 Takeaways from 'Outlive' by Peter Attia for Better Health
[2] Outlive by Peter Attia: A Book Review - Petrie-Flom Center