OT: These weight loss drugs

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Drebin

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You cannot factually prove my statement incorrect.
Well damn, I guess I'm in the wrong line of work.

That said, when you say something embarrassingly wrong and then your response is "you cannot factually prove my statement incorrect," you've lost the argument. You're the one who said the stupid thing. The burden of proof is on you.
 
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dorndawg

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People that shame others for taking meds to lose weight are being ignorant honestly.

Just because losing weight for someone else is easy doesn’t mean it is for others. The best description I’ve seen for GLP1 meds is it cuts out the food noise which is an addiction for many that they can’t cut out.
I really think it's pretty simple hatin'-asss-hater behavior, in the same vein there's always a few miserable people who cannot stand to see someone else do better for themselves.
 

johnson86-1

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I really think it's pretty simple hatin'-asss-hater behavior, in the same vein there's always a few miserable people who cannot stand to see someone else do better for themselves.
There is some of that, but there is also I think a not unhealthy bias to view drugs as a last resort rather than a first one. I do think there are a lot of wine mom's popping prozac and xanax rather than trying to address the issues causing them to want to pop pills, and I think that's a little ridiculous. I think it's also a little crazy to jump to a drug before trying some low carb eating and exercise. And I think people with that bias judge people as to weak willed to try lifestyle changes before going to drugs.

And I'm basically in that group. In particular, just tracking what you eat would I believe knock out at least morbid obesity for 99% of the population. Basically everybody that has claimed they have tried calorie restriction and it didn't work is lying and they leave stuff out of their food tracking. I'd be more sympathetic to just saying, I feel like I'm starving when I try to eat fewer calories and don't want to focus on high satiety foods because that's not what I want to eat.

But that said, the line between a supplement and drug is pretty thin in some ways. And mostly I'm just tired of having to look at whales in swimsuits, so I'm perfectly good with anybody with even an extra 10-15 lbs getting on it and the government subsidizing it if necessary.
 

dorndawg

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There is some of that, but there is also I think a not unhealthy bias to view drugs as a last resort rather than a first one. I do think there are a lot of wine mom's popping prozac and xanax rather than trying to address the issues causing them to want to pop pills, and I think that's a little ridiculous. I think it's also a little crazy to jump to a drug before trying some low carb eating and exercise. And I think people with that bias judge people as to weak willed to try lifestyle changes before going to drugs.

And I'm basically in that group. In particular, just tracking what you eat would I believe knock out at least morbid obesity for 99% of the population. Basically everybody that has claimed they have tried calorie restriction and it didn't work is lying and they leave stuff out of their food tracking. I'd be more sympathetic to just saying, I feel like I'm starving when I try to eat fewer calories and don't want to focus on high satiety foods because that's not what I want to eat.

But that said, the line between a supplement and drug is pretty thin in some ways. And mostly I'm just tired of having to look at whales in swimsuits, so I'm perfectly good with anybody with even an extra 10-15 lbs getting on it and the government subsidizing it if necessary.
Obviously I've never met you that I'm aware of, but I hear similar things from folks who haven't ever struggled with their weight. Again not directed at you in particular, but I almost wonder if some of them are terrified of losing their own "special-ness" if there's less fat folks.

In short, yeah, just about everybody has some kinda shiit they need to work on. Myself, certainly.
 
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johnson86-1

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Obviously I've never met you that I'm aware of, but I hear similar things from folks who haven't ever struggled with their weight. Again not directed at you in particular, but I almost wonder if some of them are terrified of losing their own "special-ness" if there's less fat folks.
I'm sure some of the people, particularly women, that watch what they eat and work out regularly to stay in shape are consciously or subconsciously worried/annoyed that a very valuable trait that signals self control and discipline and is valued asthetically that they have had to work for is about to be devalued. I don't care about that and am happy for people to get skinny however. I have just been radicalized by having to look at fat women in bikinis too many times. Also doesn't help seeing all the people that have eaten themselves into disability. I get not being motivated to look good, but it's somewhat horrifying to me to see people that aren't even motivated by being able to walk through the grocery store without assistance.

I definitely have a lot of sympathy for people in their 40's and older that may have made the mistake of listening to government guidelines on diet, which probably did make it really hard to stay fit if you weren't genetically gifted and/or working out all the time. I feel like for people younger than that there has been plenty of opportunity to learn that the food pyramid was basically upside down, but going off memory of when the Adkins and south beach and other diets became popular enough for people to realize something was wrong with the government messaging.



In short, yeah, just about everybody has some kinda shiit they need to work on. Myself, certainly.
true story.
 
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dudehead

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I lost 60# this way. I also recognize that it’s not that simple for a lot of people. Especially if their hormones are 17’d.
Are you still taking them? I saw my doc today for my annual checkup and asked him about it and he said "do you want to stay on it permanently because if you quit you'll probably gain the weight back." I'm curious if folks can keep the weight off if they stop taking the meds.
 
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I was hoping there would be some progress on this front, as RFK Jr. is apparently a big fan of peptides in general (though not necessarily GLP1s), so I'd hoped there would be approvals for the more-commonly-accepted ones like TB4/500 and BPC157. Of all the things I cringe about with him, this was a bright spot - but nothing I'm aware of yet.
Well thank God a world renowned medical expert is a fan. At least it's not some conspiracy theorist who was tapped to run a major federal department overseeing this type of stuff. Fortunately, Fox was out of TV personalities for the role, and we were able to get this genius.
 

johnson86-1

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Are you still taking them? I saw my doc today for my annual checkup and asked him about it and he said "do you want to stay on it permanently because if you quit you'll probably gain the weight back." I'm curious if folks can keep the weight off if they stop taking the meds.
Supposedly 25% keep the weight off and 50-55% keep some of the weight off. He seems to be definitely correct based on the record so far, but only having a 25% chance to keep a life changing amount of weight off seems like a bad reason to not prescribe it if the patient has indicated they've done all they're going to do as far as lifestyle changes.
 

OG Goat Holder

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a very valuable trait that signals self control and discipline and is valued asthetically that they have had to work for is about to be devalued.
I mean, according to the earlier pics in the thread I don't think it will be too difficult to spot folks like that.
 

Dawgbite

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Are you still taking them? I saw my doc today for my annual checkup and asked him about it and he said "do you want to stay on it permanently because if you quit you'll probably gain the weight back." I'm curious if folks can keep the weight off if they stop taking the meds.
No personal experience but have a family member who’s constantly yo-yoing. She never was fat but after children probably added 30-40 pounds. Started the shot and dropped too much weight. Face looked 10 years older. Quit the shot and in six months was back to higher weight. Started the shot again, same results stop, start. I see her a couple of times a year and you never know which one you’re going to see.
 

HailStout

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People that shame others for taking meds to lose weight are being ignorant honestly.

Just because losing weight for someone else is easy doesn’t mean it is for others. The best description I’ve seen for GLP1 meds is it cuts out the food noise which is an addiction for many that they can’t cut out.
I have had patients that have lost weight on the drugs and it has been life changing for them. They had severe underlying heart / lung problems and couldn’t exercise to the degree they needed to. This contributed to weight gain and a vicious cycle started. With the weight loss they have been able to exercise more and improve their overall quality of life. Do I like it when the soccer mom takes it for cosmetic reason? Of course not, but they are benefiting a lot of people.
 
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johnson86-1

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Well thank God a world renowned medical expert is a fan. At least it's not some conspiracy theorist who was tapped to run a major federal department overseeing this type of stuff. Fortunately, Fox was out of TV personalities for the role, and we were able to get this genius.
I mean, he's definitely not my ideal pick but we've had a crack pot, unscientific food pyramid and known it for at least two decades and it for some reason took Kennedy to try to fix it. it's kind of funny to see people get worked up over him when we've been so bad in the past.

Also, lots of people complaining about Kennedy were pretty quiet when this guy was promoting much more harmful policies. I don't know why our federal agencies are so corrupt and inept, but since we are apparently incapable of keeping bureaucracies non-partisan and science based, it's probably a good idea to shake them up to at least slow down the insanity on any one issue.

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johnson86-1

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I have had patients that have lost weight on the drugs and it has been life changing for them. They had severe underlying heart / lung problems and couldn’t exercise to the degree they needed to. This contributed to weight gain and a vicious cycle started. With the weight loss they have been able to exercise more and improve their overall quality of life. Do I like it when the soccer mom takes it for cosmetic reason? Of course not, but they are benefiting a lot of people.
As someone who spends too much time at soccer fields, stop being a selfish, narrow minded *** hole and think about the benefits to the rest of us.
 

HailStout

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I mean, he's definitely not my ideal pick but we've had a crack pot, unscientific food pyramid and known it for at least two decades and it for some reason took Kennedy to try to fix it. it's kind of funny to see people get worked up over him when we've been so bad in the past.

Also, lots of people complaining about Kennedy were pretty quiet when this guy was promoting much more harmful policies. I don't know why our federal agencies are so corrupt and inept, but since we are apparently incapable of keeping bureaucracies non-partisan and science based, it's probably a good idea to shake them up to at least slow down the insanity on any one issue.

View attachment 1173951
He could start by not telling Americans that doctors are the bad guys.

 
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I mean, he's definitely not my ideal pick but we've had a crack pot, unscientific food pyramid and known it for at least two decades and it for some reason took Kennedy to try to fix it. it's kind of funny to see people get worked up over him when we've been so bad in the past.

Also, lots of people complaining about Kennedy were pretty quiet when this guy was promoting much more harmful policies. I don't know why our federal agencies are so corrupt and inept, but since we are apparently incapable of keeping bureaucracies non-partisan and science based, it's probably a good idea to shake them up to at least slow down the insanity on any one issue.

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He was and idiot and so is Kennedy. Kennedy might actually be worse.

And the food pyramid had been gone for almost 20 years before they dug it up and came up with the upside down BS that’s probably even more confusing because what they’re promoting eating doesn’t even fit the guidelines they published along with it. The whole thing is a mess. The lemmings just eat it up because Kennedy and his merry band of grifter buddies came up with it. Might I add, go look at their conflict of interests for everyone involved. All their supporters scream that the system is biased because of conflicts of interest but these jackasșes are just as bad with their own conflicts.
 
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Drebin

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He was and idiot and so is Kennedy. Kennedy might actually be worse.

And the food pyramid had been gone for almost 20 years before they dug it up and came up with the upside down BS that’s probably even more confusing because what they’re promoting eating doesn’t even fit the guidelines they published along with it. The whole thing is a mess. The lemmings just eat it up because Kennedy and his merry band of grifter buddies came up with it. Might I add, go look at their conflict of interests for everyone involved. All their supporters scream that the system is biased because of conflicts of interest but these jackasșes are just as bad with their own conflicts.
I thought you'd love Kennedy now that he says it's safe to eat McDonalds aGAIN**

 

MississippiTexan

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Are you still taking them? I saw my doc today for my annual checkup and asked him about it and he said "do you want to stay on it permanently because if you quit you'll probably gain the weight back." I'm curious if folks can keep the weight off if they stop taking the meds.
The people I know who have taken it and lost weight have gone down to a maintenance dose. Basically you rev up doses at the beginning until you get to a high enough dose to where you are losing weight. Then once you've hit your goal, you titrate down in doses until you get to your maintenance dose. So yes, they plan to take it forever, but it's a lower dose and not as frequently. Just enough to keep it in your system and help maintain the weight loss.
 
Nov 16, 2005
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The people I know who have taken it and lost weight have gone down to a maintenance dose. Basically you rev up doses at the beginning until you get to a high enough dose to where you are losing weight. Then once you've hit your goal, you titrate down in doses until you get to your maintenance dose. So yes, they plan to take it forever, but it's a lower dose and not as frequently. Just enough to keep it in your system and help maintain the weight loss.
This is how it should be done.

Also think of it this way especially if you’re someone on medication for high BP, diabetes, cholesterol etc. if you lose the weight then it will help these issues greatly to the point you might can reduce those medications…medications you were going to be on for the rest of your life…like the weight loss drug.
 

mcdawg22

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Supposedly 25% keep the weight off and 50-55% keep some of the weight off. He seems to be definitely correct based on the record so far, but only having a 25% chance to keep a life changing amount of weight off seems like a bad reason to not prescribe it if the patient has indicated they've done all they're going to do as far as lifestyle changes.
I’d say that’s probably the same for any diet. Hell I remember when I did Keto and felt great and the pounds just fell off. Went home for Easter with all of the food that entails and that carb crave came back with a vengeance. Gained it all back plus a few for good measure.
 

johnson86-1

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He could start by not telling Americans that doctors are the bad guys.



He could be way worse than I think because I tune so much politics out, so this isn't really related to him, but looking from the outside in, the problem with doctors is that most of them just want to operate within the existing rules and at best are willing to sacrifice some of their income to provide a better experience and care to their patients, or at worst just maximize the money and lifestyle tradeoffs inherent in the system an to hell with the patient experience as they (not entirely unfairly) feel like they weren't the ones that designed the system .

And the few that provide any input into policy and are effective, are uniformly doing so in a manner that restricts supply. So we have consistently grown medical school and residency spots at slower than the population, while advocating against allowing nurse practitioners or PAs more freedom to practice without oversight, advocating against limiting undergrad requirements for med school applicants, advocating against admission of foreign trained doctors without attending an entirely new residency, etc. Sometimes you do see them argue against CON laws, but generally only when they are held back by them, not as a matter of principle. And then everyone scratches their heads and wonder why healthcare has gotten so much more expensive, and then blame insurance and pharmaceutical companies (neither of which are innocent, but are mostly just operating within the rules as they exist, with the exception of insurance companies that advocated for mandatory health insurance under obamacare).

It's a weird dynamic where individually, doctors are probably better than lawyers (or at least there are many fewer absolute slimeballs), but if you just looked at how effectively the professions engage in economic protectionism, you'd think doctors were the greedy leeches on society.
 
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I have lost 50 lbs on zepbound. Started on ozempic but had side effects. It definitely works but there have been periods over the last 3 years where I got lazy and or forgot to refill it and I went a month or 2 without it. That appetite comes roaring back. I gained 15 lbs the last “break” I took. Unless you are disciplined and eat right/exercise you will gain it all back quickly.
i lost 35 on zepbound and got down to 180.....now I use the zepbound as a maintenance 2x a month....yes, the appetite comes roaring back....if you didnt learn to eat well while doing the jab, you are just a temporary.....i feel better, look better, and, my pecker got bigger....better to be skinny and unhealthy rather than fat and unhealthy as someone said earlier....no loss on muscle mass as someone said earlier but i go to the gym 4-5x week.
 
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Dawgbite

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I love food. It’s one of the few pleasures in life that don’t hurt or make me sore. I’ve just resigned myself to being 25 pounds over what the chart says is my ideal weight.
 
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GloryDawg

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I don't shame people, but I do believe walking is way less expensive and probably better long-term health.
 

HailStout

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He could be way worse than I think because I tune so much politics out, so this isn't really related to him, but looking from the outside in, the problem with doctors is that most of them just want to operate within the existing rules and at best are willing to sacrifice some of their income to provide a better experience and care to their patients, or at worst just maximize the money and lifestyle tradeoffs inherent in the system an to hell with the patient experience as they (not entirely unfairly) feel like they weren't the ones that designed the system .

And the few that provide any input into policy and are effective, are uniformly doing so in a manner that restricts supply. So we have consistently grown medical school and residency spots at slower than the population, while advocating against allowing nurse practitioners or PAs more freedom to practice without oversight, advocating against limiting undergrad requirements for med school applicants, advocating against admission of foreign trained doctors without attending an entirely new residency, etc. Sometimes you do see them argue against CON laws, but generally only when they are held back by them, not as a matter of principle. And then everyone scratches their heads and wonder why healthcare has gotten so much more expensive, and then blame insurance and pharmaceutical companies (neither of which are innocent, but are mostly just operating within the rules as they exist, with the exception of insurance companies that advocated for mandatory health insurance under obamacare).

It's a weird dynamic where individually, doctors are probably better than lawyers (or at least there are many fewer absolute slimeballs), but if you just looked at how effectively the professions engage in economic protectionism, you'd think doctors were the greedy leeches on society.
if you think doctors are the reason healthcare is so expensive, I don’t know what to tell you. I don’t want to get on my soapbox, so I will leave it at that
 

johnson86-1

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if you think doctors are the reason healthcare is so expensive, I don’t know what to tell you. I don’t want to get on my soapbox, so I will leave it at that
Restricting supply is not the only reason healthcare is expensive (although it's a major part) and we haven't put a chokehold on supply solely at the request of doctors (some of it is just not wanting to fund residencies although the 1997 cap on was basically at the request of the AMA is my understanding), but to the extent doctors weigh in on it, they have historically been on the wrong side. Again, most doctors just don't get involved on the policy side, so I'm certainly not blaming individual doctors, but as a group, they've been extremely successful at turning good will towards doctors into economic protectionism that hurts patients and affordability.
 
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mstateglfr

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I mean, he's definitely not my ideal pick but we've had a crack pot, unscientific food pyramid and known it for at least two decades and it for some reason took Kennedy to try to fix it. it's kind of funny to see people get worked up over him when we've been so bad in the past.

Also, lots of people complaining about Kennedy were pretty quiet when this guy was promoting much more harmful policies. I don't know why our federal agencies are so corrupt and inept, but since we are apparently incapable of keeping bureaucracies non-partisan and science based, it's probably a good idea to shake them up to at least slow down the insanity on any one issue.
The Food Pyramid ended 15 years ago. It was replaced with MyPlate. MyPlate is shown below.
The Food Funnel, what Kennedy released recently, is a jumbled confusion that seems to prioritize saturated fat since dairy and beef animal proteins are so heavily emphasized.

Kennedy has clearly been harmful to the overall health knowledge in the US. And he has hurt medical progress globally. He constantly just tries to sow doubt while speaking out of both sides of his mouth and claiming he isnt doing the very thing he is doing. It is yet another form of chaos- it is a persistant chipping away at trust in the very institution he represents. And what he typically offers as an alternative are debunked claims and misunderstood studies.

- Cane sugar isnt any healthier than HFCS.
- His dismantling of research has set medical progress back.
- The constant support of vaccines while quietly not supporting vaccines is detrimental.
- Picking vax crazies to be on an Audism Advisory Board is bonkers.
- Germs in fact can make you sick.
- AIDS is actually a result of HIV.
- Lyme disease is not known to be a lab leak.


I find your seemingly flippant viewpoint of 'might as well balance the crazy if it cant be stopped' to be highly dangerous. No, no that is not how we should handle health related research and guidance in this country. That isnt how human health and food safety divisions within the government should operate.
Lies have been allowed to grow like weeds and we have too few people available to pull em all at the root, so many grow bigger. That is the real issue. That is what needs to be stopped. Conspiracies and lies need to be called out as such by everyone and not given equal time by media organizations.

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PBRME

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I love food. It’s one of the few pleasures in life that don’t hurt or make me sore. I’ve just resigned myself to being 25 pounds over what the chart says is my ideal weight.
I exercise to be able to eat what I want.
 
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I mean, he's definitely not my ideal pick but we've had a crack pot, unscientific food pyramid and known it for at least two decades and it for some reason took Kennedy to try to fix it. it's kind of funny to see people get worked up over him when we've been so bad in the past.

Also, lots of people complaining about Kennedy were pretty quiet when this guy was promoting much more harmful policies. I don't know why our federal agencies are so corrupt and inept, but since we are apparently incapable of keeping bureaucracies non-partisan and science based, it's probably a good idea to shake them up to at least slow down the insanity on any one issue.

View attachment 1173951
Whataboutism...great argument. So you admit Kennedy is a moron, but it's ok as long as other were morons too. Got it.
 
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L4Dawg

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Restricting supply is not the only reason healthcare is expensive (although it's a major part) and we haven't put a chokehold on supply solely at the request of doctors (some of it is just not wanting to fund residencies although the 1997 cap on was basically at the request of the AMA is my understanding), but to the extent doctors weigh in on it, they have historically been on the wrong side. Again, most doctors just don't get involved on the policy side, so I'm certainly not blaming individual doctors, but as a group, they've been extremely successful at turning good will towards doctors into economic protectionism that hurts patients and affordability.
Hot garbage
 
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johnson86-1

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Whataboutism...great argument. So you admit Kennedy is a moron, but it's ok as long as other were morons too. Got it.
It's not "ok", but I'm not going to get my panties in a wad about the HHS continuing to be bad after the prior administration just set fire to their credibility and public trust. I mean, that's awful and if we have another pandemic it's going to be way worse than it should because public trust in public health related institutions is a huge asset that we shredded for no good reason, but even if we cleaned house and somehow made our public health institutions trustworthy, that alone won't restore trust. It's going to take time regardless. Maybe we'll start treating it seriously in the future and in another 10 to 15 years after that, we'll have trustworthy institutions that are also trusted.

But it is worth noting that somewhere well north of 90% of the people complaining about Kennedy don't actually care about HHS either, because if they did they would have been losing their mind over Leavitt and the incompetence HHS and the organizations under its umbrella during COVID, and hell, FDA and CDC have been awful for years before that too.
 
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L4Dawg

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If there is a more reliable indicator of being right on this board than you strongly disagreeing, I'd love to see it.

But also love the reasoned take disproving basic economics.
Restricting supply basically doesn't happen, and in the very few places where it does it's not even CLOSE to being the main reason healthcare is expensive. Walk through a dang hospital and look around. If you are old enough think back to what it looked like 40-50 years ago. Then go take a look at the insurance and government bureaucracy that is also being supported by those at the point. Compare THAT to 40-50 years ago. Those are the real biggies, but there are many other things ahead of your fantasy.
 
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