Sam Horn injury update: Missouri QB reportedly out indefinitely pending MRI results

Missouri quarterback Sam Horn underwent an MRI on Friday after suffering a lower leg injury in Missouri’s 61-6 season-opening win over Central Arkansas. He is out indefinitely, pending the results of additional testing, per ESPN‘s Pete Thamel.

There is still some uncertainty, though. Clarity on the timeline is expected in the upcoming days, per Thamel.

Sources: Missouri QB Sam Horn underwent an MRI today after suffering a lower leg injury in Missouri’s opener. He’s out indefinitely, pending the results of additional testing. Clarity on the timeline is expected in the upcoming days. pic.twitter.com/OOcQCnU7Mb

— Pete Thamel (@PeteThamel) August 29, 2025

Horn took his first snap of the game with 5:19 remaining in the first half and was tackled low by Central Arkansas DB Dude Person following a six-yard run. He attempted to walk after the tackle, but collapsed to the turf and had to be assisted off the field by team personnel.

Missouri head coach Eli Drinkwitz was pressed for an update on Horn following the win. The Tigers are now 5-2 in season openers under Drink.

“Is it expected to be (a long-term injury)? Yeah, I’m not gonna speculate,” Drinkwitz responded. “I don’t have a doctorate degree. They’ll find out tomorrow when they get an MRI.” 

Quarterback Beau Pribula stepped up in a big way following the Horn injury. He made a great first impression on Missouri fans, as he completed 23/28 passes for 283 yards and two touchdowns. He also totaled 65 rushing yards and two scores on the ground.

Drinkwitz applauds Pribula for stepping up following Horn injury

“I don’t think (Beau Pribula) stepped up, I think he just continued to play the way he’s been playing,” Drinkwitz continued. “I thought he did a nice job handling the situation. He knew he was gonna play the first half and we knew we were gonna run that formation pretty early in the game. Just disappointing that (Sam Horn) got injured. It was a heck of a run so it’s disappointing.”

“I was pleased because I knew (Pribula) prepared well in fall camp and I tried to tell everybody that we had two quarterbacks that can win football games and I fully expected that to be the case. He played honestly pretty well and I thought Sam played pretty well too. I thought his ability to extend plays (that one big run was pretty headsey there) and his ability to pull the ball on some zone read stuff was nice. But he threw the ball really well so it was good.”

Missouri will be back in action on Sept. 6 in a rivalry matchup against Kansas. Kick-off is scheduled for 3:30 PM on ESPN2.