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Final Four: Hypothetical national championship game odds released for every matchup

IMG_6598by: Nick Kosko03/31/25nickkosko59

With the Final Four now set, the odds are in for hypothetical national championship games in March Madness. There are four possibilities between the four No. 1 seeds.

Sure there was chalk this year, getting to San Antonio and fighting for the ultimate prize. But, college basketball fans should be treated to some high quality games.

As it stands, we get a Florida–Auburn matchup as they run back an SEC game in the first one of the night. Then, we get Houston vs. Duke on the other side and it all goes down Saturday, April 5th. Here are the odds for each hypothetical matchup, per FanDuel.

Duke vs. Auburn

Spread: Duke (-4.5)
Moneyline: Duke (-205), Auburn (+168)
Total: 153.5

These two teams actually met once already and could meet again for the national championship. The Blue Devils won the initial meeting in December, 84-78.

Houston vs. Auburn

Troy Taormina-Imagn Images

Spread: Auburn (-1.5)
Moneyline: Auburn (-113), Houston (-106)
Total: 138.5

Auburn and Houston had a very early meeting this season as you have to go back to November. The Tigers beat the Cougars 74-69 and this matchup is razor thin close, should it happen again. Vegas can barely decide on this potential national championship game!

Florida vs. Houston

Spread: Florida (-1.5)
Moneyline: Florida (-114), Houston (-105)
Total: 143.5

These two teams did not face each other in the regular season and Vegas doesn’t know which way to go. Well, they lean slightly towards the Gators, but if Houston is in the national championship, it’s going to be very hard to predict a winner.

Florida vs. Duke

Duke coach Jon Scheyer
Duke coach Jon Scheyer (Robert Deutsch / Imagn Images)

Spread: Duke (-4.5)
Moneyline: Duke (-194), Florida (+160
Total: 159.5

Maybe the matchup that everyone wants to see, but Duke is a bigger favorite than everyone else, should the Blue Devils make the national championship. These two teams did not play each other during the regular season.

The Final Four is scheduled for April 5th at 6:09 p.m. ET and 8:49 p.m. ET. The national championship is scheduled for April 7th at 8:50 p.m. ET.