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On Kentucky’s second drive of the game, a third and 10 allowed the Louisville defense to gear up for one of the day's many creative pass rush

Wesley Bailey, Clev Lubin and Louisville celebrate sack in 41-0 win over Kentucky.

Louisville Cardinals defensive lineman Clev Lubin (50) celebrates his sack of Kentucky quarterback Cutter Boley with Louisville Cardinals defensive lineman Wesley Bailey (23) as the Cards roll past the Cats 41-0 Saturday, November 29, 2025.

Cardinal Sports

Louisville's defense gets its finish against Kentucky, proves to be worthwhile investment

Kentucky (5-6, 2-6) is stepping out of conference play to end the 2025 regular season. The Wildcats will be looking to sweep the non-conference on

Louisville’s coach Jeff Brohm brings his team out onto the field against Virginia at L&N Stadium Saturday. Oct. 4, 2025. © Scott Utterback/Courier Journal / USA TODAY NETWORK via Imagn Images

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Scouting Report: Louisville Cardinals

For the first time since returning to his alma mater, Louisville has lost back-to-back home games under Jeff Brohm, after falling 20-19 to Clemson on

Nov 14, 2025; Louisville, Kentucky, USA; Louisville Cardinals kicker Nick Keller (98) reacts after missing a field goal attempt during the second half against the Clemson Tigers at L&N Federal Credit Union Stadium. Clemson defeated Louisville 20-19. Mandatory Credit: Jamie Rhodes-Imagn Images

Cardinal Sports Football

How it happened: No. 20 Louisville controlled own fortune in 20-19 loss to Clemson

Well, that was weird.   In a game that spanned almost four hours, there was a little bit of everything in No. 19 Louisville's 38-28 win over Boston

Oct 25, 2025; Louisville, Kentucky, USA; Louisville Cardinals running back Keyjuan Brown (22) runs the ball for a touchdown against the Boston College Eagles during the second half at L&N Federal Credit Union Stadium. Mandatory Credit: Jamie Rhodes-Imagn Images

How it happened: No. 19 Louisville stumbles past Boston College

Louisville relied on its defense to complete the 24-21 upset over No. 2 Miami.   The Cards came into Hard Rock Stadium and secured a program-defining

Oct 17, 2025; Miami Gardens, Florida, USA; Miami Hurricanes wide receiver Keelan Marion (0) carries the football against Louisville Cardinals linebacker Kalib Perry (12) during the third quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-Imagn Images

Louisville showcases defensive masterpiece in upset win over Miami

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Louisville's defense gets its finish against Kentucky, proves to be worthwhile investment

Scouting Report: Louisville Cardinals

How it happened: No. 20 Louisville controlled own fortune in 20-19 loss to Clemson

How it happened: No. 19 Louisville stumbles past Boston College

Louisville showcases defensive masterpiece in upset win over Miami

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