For those interested in biotech. Cut and paste due to a paywall. Bottom?
________________________________________
A record number of small biotechs are now trading below cash. Is this the bottom yet? | Endpoints News | May 9, 2022
For anyone who’s been following biotech news of late, it should be no surprise that many small- to mid-cap players are struggling. But the scope and depth of their troubles may be harder to grasp.
Jefferies analysts took a stab at quantifying the market downturn and came up with a number: 128 companies are now trading at a market cap smaller than the cash they have on hand, a “historical” number owing to negative clinical events, negative FDA developments and macro economic environments.
The observation adds to other indicators of a daunting bear market, from numerical ones such as plummeting biotech indices to anecdotal evidence of individual companies executing major reorganizations, layoffs, pipeline pivots, or even seeking the dreaded “strategic alternatives.”
Although they predict that 2022 will remain a tough year overall, Michael Yee, Dennis Ding, Andrew Tsai and their team do hope that the second half of the year may bring some respite — particularly if Big Pharma steps up on M&A. As they remarked days ago, the top 15 drugmakers have enough cash to buy out the whole SMID biotech sector, or a whopping 644 companies.
Looking back at the past 15 years, the analysts noted that since 2007, the number of SMID cap biotechs trading below cash has never gone higher than 45. In fact, for the most part, fewer than 20 biotechs each year fell to that predicament.
Sure, SMID cap biotechs these days do have more cash than earlier years “to keep up with a higher burn,” they wrote.
“(H)owever, we note a faster pace of market value contraction in SMID caps (all cap $0-5B) with now over 120 companies trading below cash vs ~45 in YE:21 and on average ~10-20 smids for the past 15 years,” the Jefferies note read.
Perhaps more important, not only is 128 the highest number they’ve seen, at 25% it’s also the “highest percent share of the industry.” That’s up there with the 2008-2009 period, just after the financial tsunami.
One factor, they noted, is the macro environment pushing generalist investors into “defensive, dividend-yielding large-cap” names, leaving little on the table for the lesser-known names. Then there was the stream of bad news — negative readouts — that inevitably trigger falls, and regulatory moves, such as delays and clinical holds, that might suggest a harsher environment.
Still, things could improve if coming clinical updates turn out positive, and they believe IPO activity will pick up again near the end of the year “with more conservative valuations.”
As to whether M&A activity will pick up, they are calling it possible without speculating too much. However, we sense the buyer-seller spread may keep widening until the market finds bottom. Additionally, this doesn’t mean the companies trading below cash are going to be taken out soon – they likely suffered from negative events. As we have repeatedly said, sentiment is unlikely to turn on a few small deals and investors are watching for big ones (at least $5B in our view).