Heisman Trophy Odds: Ranking betting favorites in college football after Week 10

The 2025 college football season is officially on the backstretch of the regular season as the calendar turns the page to November. And with that, the 2025 Heisman Trophy race is rounding into form as the once expansive field of contenders becomes a four-horse race entering Week 11 of the regular season.

And to no one’s surprise, that tightening Heisman Trophy field is filled by the quarterbacks of Top 4 ranked teams following a wild Week 10. That includes the brand-new betting favorite, Ohio State QB Julian Sayin, who ascended to the top spot after a near-perfect performance in Saturday’s 38-14 win over Penn State. In fact, Sayin is the odds-on favorite with +175 odds, up from +400 a week ago, with just four players currently receiving +750 or better odds, according to BetMGM. There’s actually a 1,250-point differential between the fourth and fifth best odds in the field.

With that in mind, check out BetMGM’s latest odds to win the 2025 Heisman Trophy after Week 10:

Julian Sayin, QB, Ohio State (+175, was +400)

The Buckeyes’ redshirt freshman signal caller became the new betting favorite within minutes of his immaculate performance against the Nittany Lions, when he threw for more touchdowns (four) than incompletions (three) while going 20-of-23 for 316 yards and four scores Saturday.

It was Sayin’s second-consecutive four-TD game and cemented himself as college football’s most accurate passer this season with a nation’s-leading 80.7 completion percentage, more than seven points better than the next closest contender.

Fernando Mendoza, QB, Indiana (+225, was +325)

The Hoosiers’ junior signal-caller continues to turn heads and open eyes in his first season in Bloomington, and holds down the No. 2 spot in the field due to his sheer consistency at the position, leading Indiana to a second-straight 9-0 start to the regular season.

Despite not filling the stat sheet Saturday, Mendoza’s 25 touchdowns this season rank second nationally, as does his 185.23 quarterback rating, just behind Sayin’s FBS-leading 197.11. As long as the Hoosiers keep winning, Mendoza’s place in NYC for next month’s Heisman ceremony is all-but certain.

Ty Simpson, QB, Alabama (+350, was +325)

With his team on bye last weeked, Simpson fell from first to third in BetMGM’s latest Heisman odds, effectively switching spots with his former Crimson Tide teammate (Sayin). Of course, Alabama’s junior QB still leads the SEC with a 162.63 QB rating and ranks second with 20 touchdowns to one interception.

And with high-profile games ahead against LSU, No. 11 Oklahoma and the Iron Bowl against an Auburn squad that just fired head coach Hugh Freeze, there’s plenty of time for Simpson to make his case to the Heisman Trophy voters down the stretch.

Marcel Reed, QB, Texas A&M (+750, was +550)

A week after leapfrogging into the Top 5 in BetMGM’s Heisman odds, the Aggies’ sophomore QB falls back slightly while his team was on bye, but still holds onto the fourth-best odds by a wide-margin.

Reed has been electric in his first full season as Texas A&M’s starting quarterback, ranking third in the SEC averaging 290.1 yards of total offense per game while also ranking second averaging nearly 8.1 yards per play this season. Reed’s 23 total touchdowns this season also ranks third in the SEC.

Gunner Stockton, QB, Georgia (+2000, was +1500)

The great divide in the latest Heisman odds starts at No. 5 with Georgia’s junior quarterback, who once again saved the Cardiac ‘Dawgs with another fourth-quarter comeback drive to secure Saturday’s 24-20 win over rival Florida.

With 223 yards and two passing scores, Stockton produced his third-straight game with at least 200 yards passing and second with multiple touchdowns. Stockton leads the SEC with a 70.3 completion percentage to go along with 2,066 total yards and 19 combined touchdowns to just two interceptions

Diego Pavia, QB, Vanderbilt (+2500, was +800)

The talk of the SEC for the second-straight season, Pavia’s Heisman odds took a big hit following the Saturday’s 34-31 loss to Texas in Austin. Despite the setback, the Commodores’ sixth-year QB still filled the stat sheet with 408 total yards and four touchdowns in the game.

Through nine games, Pavia ranks third in the SEC with 2,564 yards of total offense and second in the league with 24 total touchdowns, including 501 rushing yards and six scores on the ground to rank second in rushing among SEC quarterbacks.

Trinidad Chambliss, QB, Ole Miss (+3500, was +2000)

After starting the season as the Rebels’ backup, Chambliss stepped up in place of an injured Austin Simmons and quickly established himself a an electric playmaker, so much so he currently ranks fourth in the SEC with 2,458 yards of total offense through nine games.

Still, Chambliss’ Heisman odds took a hit after struggling through his worst offensive performance as Ole Miss’ starter, with just 159 yards on 57.1-percent passing and one touchdown to one interception in Saturday’s 30-14 win over South Carolina.

Jeremiah Smith, WR, Ohio State (+4000, was +3000)

The Buckeyes’ superstar receiver continues to hold down the spot as the highest-ranked non-quarterback in BetMGM’s latest Heisman Trophy odds, even if those odds fell slightly as the field has tightened around its Top 4 favorites — all quarterbacks.

Of course, Smith’s slide has nothing to do with production after the 6-foot-3, 215-pound wideout led Ohio State with two touchdowns on a team-high six receptions and 123 yards in Saturday’s 38-14 win over Penn State. Smith currently leads the Big Ten with 55 catches for 725 yards and nine touchdowns.

Dante Moore, QB, Oregon (+4000, no change)

The Ducks’ redshirt sophomore quarterback struggled with a season-low 86 passing yards and no touchdowns in Saturday’s 21-7 win over Wisconsin, but still holds onto a Top 10 spot in BetMGM’s Heisman odds after leading Oregon to a second-straight victory.

Moore’s Heisman odds have taken a hit since the Ducks’ Week 7 home loss to Indiana, but outside of Saturday’s performance, he’s been fairly consistent, including ranking third in the Big Ten with a 171.1 quarterback rating and fifth with a 71.4 completion percentage.

Jeremiyah Love, RB, Notre Dame (+4000, was +1800)

The Fighting Irish’s leading rusher fell into a three-way tie for eighth in BetMGM’s latest Heisman odds despite another huge game on the field after rushing for 136 yards and two scores in Saturday’s 25-10 road win over host Boston College.

Love’s 894 rushing yards through eight games ranks sixth nationally to go along with 11 rushing scores to tie for fifth in the FBS this season. While a trip to NYC is unlikely at this point, a potential Playoff bid will be a nice consolation prize for both Notre Dame and Love.

Haynes King, QB, Georgia Tech (+5000)
CJ Carr, QB, Notre Dame (+6000)
John Mateer, QB, Oklahoma (+10000)
Miller Moss, QB, Louisville (+10000)
Jayden Maiava, QB, USC (+10000)
Carson Beck, QB, Miami (+10000)

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